2VH0 PDB NFT

Structure and property based design of factor Xa inhibitors:biaryl pyrrolidin-2-ones incorporating basic heterocyclic motifs

MOLNFT AF v1 smart contract in GenesisL1 blockchain:

0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba

IPFS of NFT metadata:

bafybeiblb4curuwuj2l4mxrkwhesvfas2d7lbnmtngvyq6u5dac4x3i6t4/metadata.json

IPFS of structure file:

bafybeiej7vy7mrfzx7ajz7rh26ln2dw4pz7bbb7uqiwjj2qmph2wf4emxu/2vh0.pdb

MOLNFT PDB v1

NFT id:
51762
PDB ID:
2VH0
Name:
Structure and property based design of factor Xa inhibitors:biaryl pyrrolidin-2-ones incorporating basic heterocyclic motifs
Keywords:
HYDROLASE
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.70

NFT data

MolNFT PDB v1 is The Protein Data Bank database (URL: https://rcsb.org) of protein structures minted as ERC-721 NFT tokens on GenesisL1 blockchain for public free use, research and entertainment:

H.M. Berman, J. Westbrook, Z. Feng, G. Gilliland, T.N. Bhat, H. Weissig, I.N. Shindyalov, P.E. Bourne.
(2000) The Protein Data Bank Nucleic Acids Research, 28: 235-242.

MOLNFT 2VH0 research and analysis (ICN3D with VR)

FASTA sequences

>2vh0_A mol:protein length:254 ACTIVATED FACTOR XA HEAVY CHAIN
IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK
>2vh0_B mol:protein length:134 ACTIVATED FACTOR XA LIGHT CHAIN
EEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLER

References and links

Current molecular structure file and data about current molecular structure file and NFT token based on it with
PDBID: 2VH0
TITLE: Structure and property based design of factor Xa inhibitors:biaryl pyrrolidin-2-ones incorporating basic heterocyclic motifs
DOI: 10.1016/j.bmcl.2007.11.019
AUTHORS: Young, R.J., Borthwick, A.D., Brown, D., Burns-Kurtis, C.L., Campbell, M., Chan, C., Charbaut, M., Convery, M.A., Diallo, H., Hortense, E., Irving, W.R., Kelly, H.A., King, N.P., Kleanthous, S., Mason, A.M., Pateman, A.J., Patikis, A., Pinto, I.L., Pollard, D.R., Senger, S., Shah, G.P., Toomey, J.R., Watson, N.S., Weston, H.E., Zhou, P.
ACCESSION DATE: 11/16/07
Obtained at RCSB PDB https://rcsb.org
RCSB Link: https://www.rcsb.org/structure/2VH0