3UPC PDB NFT | MOLNFT bioinformatics, blockchain

A general strategy for the generation of human antibody variable domains with increased aggregation resistance

MOLNFT AF v1 smart contract in GenesisL1 blockchain:

0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba

IPFS of NFT metadata:

bafybeieb7mfwrcafgkkox34z3dgembhywh3l6ggry42x3zuior5mh7boze/metadata.json

IPFS of structure file:

bafybeighg4yq2pyssv4qdnehjvpcbvmhsk7zns5avhu5mswmwhsmev2xpi/3upc.pdb

MOLNFT PDB v1

NFT id:
81394
PDB ID:
3UPC
Name:
A general strategy for the generation of human antibody variable domains with increased aggregation resistance
Keywords:
IMMUNE SYSTEM
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.80

NFT data

MolNFT PDB v1 is The Protein Data Bank database (URL: https://rcsb.org) of protein structures minted as ERC-721 NFT tokens on GenesisL1 blockchain for public free use, research and entertainment:

H.M. Berman, J. Westbrook, Z. Feng, G. Gilliland, T.N. Bhat, H. Weissig, I.N. Shindyalov, P.E. Bourne.
(2000) The Protein Data Bank Nucleic Acids Research, 28: 235-242.

MOLNFT 3UPC research and analysis (ICN3D with VR)

FASTA sequences

>3upc_A mol:protein length:113 heavy chain variable domain
QLLESGGGLVQPGGSLRLSCAASGFTFSDEDMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKSYGAFDYWGQGTLVTVS
>3upc_B mol:protein length:113 heavy chain variable domain
QLLESGGGLVQPGGSLRLSCAASGFTFSDEDMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKSYGAFDYWGQGTLVTVS
>3upc_C mol:protein length:113 heavy chain variable domain
QLLESGGGLVQPGGSLRLSCAASGFTFSDEDMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKSYGAFDYWGQGTLVTVS
>3upc_D mol:protein length:113 heavy chain variable domain
QLLESGGGLVQPGGSLRLSCAASGFTFSDEDMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKSYGAFDYWGQGTLVTVS
>3upc_E mol:protein length:113 heavy chain variable domain
QLLESGGGLVQPGGSLRLSCAASGFTFSDEDMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKSYGAFDYWGQGTLVTVS
>3upc_F mol:protein length:113 heavy chain variable domain
QLLESGGGLVQPGGSLRLSCAASGFTFSDEDMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKSYGAFDYWGQGTLVTVS
>3upc_G mol:protein length:113 heavy chain variable domain
QLLESGGGLVQPGGSLRLSCAASGFTFSDEDMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKSYGAFDYWGQGTLVTVS
>3upc_H mol:protein length:113 heavy chain variable domain
QLLESGGGLVQPGGSLRLSCAASGFTFSDEDMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKSYGAFDYWGQGTLVTVS
>3upc_I mol:protein length:113 heavy chain variable domain
QLLESGGGLVQPGGSLRLSCAASGFTFSDEDMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKSYGAFDYWGQGTLVTVS
>3upc_J mol:protein length:113 heavy chain variable domain
QLLESGGGLVQPGGSLRLSCAASGFTFSDEDMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKSYGAFDYWGQGTLVTVS

References and links

Current molecular structure file and data about current molecular structure file and NFT token based on it with
PDBID: 3UPC
TITLE: A general strategy for the generation of human antibody variable domains with increased aggregation resistance
DOI: 10.1073/pnas.1202866109
AUTHORS: Dudgeon, K., Rouet, R., Kokmeijer, I., Langley, D.B., Christ, D.
ACCESSION DATE: 11/17/11
Obtained at RCSB PDB https://rcsb.org
RCSB Link: https://www.rcsb.org/structure/3UPC