3UI7 PDB NFT

Discovery of orally active pyrazoloquinoline as a potent PDE10 inhibitor for the management of schizophrenia

MOLNFT AF v1 smart contract in GenesisL1 blockchain:

0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba

IPFS of NFT metadata:

bafybeicmjtyh55tad52tfegldkpisxzjd3zhmno37l7tmk23n7baegae6u/metadata.json

IPFS of structure file:

bafybeicp66ng7bdun2bmbtdpaicjuhcv7ga5nicgiz5s4fmxhimej3hvcu/3ui7.pdb

MOLNFT PDB v1

NFT id:
81156
PDB ID:
3UI7
Name:
Discovery of orally active pyrazoloquinoline as a potent PDE10 inhibitor for the management of schizophrenia
Keywords:
HYDROLASE/HYDROLASE INHIBITOR
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.28

NFT data

MolNFT PDB v1 is The Protein Data Bank database (URL: https://rcsb.org) of protein structures minted as ERC-721 NFT tokens on GenesisL1 blockchain for public free use, research and entertainment:

H.M. Berman, J. Westbrook, Z. Feng, G. Gilliland, T.N. Bhat, H. Weissig, I.N. Shindyalov, P.E. Bourne.
(2000) The Protein Data Bank Nucleic Acids Research, 28: 235-242.

MOLNFT 3UI7 research and analysis (ICN3D with VR)

FASTA sequences

>3ui7_A mol:protein length:333 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
GMEKLSYHSHMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEE
>3ui7_B mol:protein length:333 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
GMEKLSYHSHMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEE

References and links

Current molecular structure file and data about current molecular structure file and NFT token based on it with
PDBID: 3UI7
TITLE: Discovery of orally active pyrazoloquinoline as a potent PDE10 inhibitor for the management of schizophrenia
DOI: 10.1016/j.bmcl.2011.11.023
AUTHORS: Yang, S., Smotryski, J., Mcelroy, W., Ho, G., Tulshian, D., Greenlee, W.J., Hodgson, R., Xiao, L., Hruza, A.
ACCESSION DATE: 11/04/11
Obtained at RCSB PDB https://rcsb.org
RCSB Link: https://www.rcsb.org/structure/3UI7