2WYJ PDB NFT

Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifs

MOLNFT AF v1 smart contract in GenesisL1 blockchain:

0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba

IPFS of NFT metadata:

bafybeic7dayvyh7a3xxn7rjfr46ybzix4qjdpnzmkpe6zysgo7afkxlynq/metadata.json

IPFS of structure file:

bafybeifq7mjma2kzo2igtmobyozguxbsyu6fs2hho3xtmy5ccphs3swuty/2wyj.pdb

MOLNFT PDB v1

NFT id:
53565
PDB ID:
2WYJ
Name:
Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifs
Keywords:
BLOOD CLOTTING
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.38

NFT data

MolNFT PDB v1 is The Protein Data Bank database (URL: https://rcsb.org) of protein structures minted as ERC-721 NFT tokens on GenesisL1 blockchain for public free use, research and entertainment:

H.M. Berman, J. Westbrook, Z. Feng, G. Gilliland, T.N. Bhat, H. Weissig, I.N. Shindyalov, P.E. Bourne.
(2000) The Protein Data Bank Nucleic Acids Research, 28: 235-242.

MOLNFT 2WYJ research and analysis (ICN3D with VR)

FASTA sequences

>2wyj_A mol:protein length:254 ACTIVATED FACTOR XA HEAVY CHAIN
IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK
>2wyj_B mol:protein length:134 FACTOR X LIGHT CHAIN
EEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLER

References and links

Current molecular structure file and data about current molecular structure file and NFT token based on it with
PDBID: 2WYJ
TITLE: Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifs
DOI: 10.1016/j.bmcl.2009.11.077
AUTHORS: Kleanthous, S., Borthwick, A.D., Brown, D., Burns-Kurtis, C.L., Campbell, M., Chaudry, L., Chan, C., Clarte, M., Convery, M.A., Harling, J.D., Hortense, E., Irving, W.R., Irvine, S., Pateman, A.J., Patikis, A., Pinto, I.L., Pollard, D.R., Roethka, T.J., Senger, S., Shah, G.P., Stelman, G.J., Toomey, J.R., Watson, N.S., Whittaker, C., Zhou, P., Young, R.J.
ACCESSION DATE: 11/16/09
Obtained at RCSB PDB https://rcsb.org
RCSB Link: https://www.rcsb.org/structure/2WYJ