2VH6 PDB NFT

Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with biaryl P4 motifs

MOLNFT AF v1 smart contract in GenesisL1 blockchain:

0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba

IPFS of NFT metadata:

bafybeib7svoeiscit5tvz6zudvxnfvvsqsyfm6edfx6i446peu44q3xvxm/metadata.json

IPFS of structure file:

bafybeidjslhrq2hbxpojwbqrarq4kiksgl752g4damj7qumnrhdnrleh74/2vh6.pdb

MOLNFT PDB v1

NFT id:
51768
PDB ID:
2VH6
Name:
Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with biaryl P4 motifs
Keywords:
HYDROLASE
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.95

NFT data

MolNFT PDB v1 is The Protein Data Bank database (URL: https://rcsb.org) of protein structures minted as ERC-721 NFT tokens on GenesisL1 blockchain for public free use, research and entertainment:

H.M. Berman, J. Westbrook, Z. Feng, G. Gilliland, T.N. Bhat, H. Weissig, I.N. Shindyalov, P.E. Bourne.
(2000) The Protein Data Bank Nucleic Acids Research, 28: 235-242.

MOLNFT 2VH6 research and analysis (ICN3D with VR)

FASTA sequences

>2vh6_A mol:protein length:254 ACTIVATED FACTOR XA HEAVY CHAIN
IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK
>2vh6_B mol:protein length:134 ACTIVATED FACTOR XA LIGHT CHAIN
EEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLER

References and links

Current molecular structure file and data about current molecular structure file and NFT token based on it with
PDBID: 2VH6
TITLE: Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with biaryl P4 motifs
DOI: 10.1016/j.bmcl.2007.11.023
AUTHORS: Young, R.J., Borthwick, A.D., Brown, D., Burns-Kurtis, C.L., Campbell, M., Chan, C., Charbaut, M., Chung, C.W., Convery, M.A., Kelly, H.A., King, N.P., Kleanthous, S., Mason, A.M., Pateman, A.J., Patikis, A.N., Pinto, I.L., Pollard, D.R., Senger, S., Shah, G.P., Toomey, J.R., Watson, N.S., Weston, H.E.
ACCESSION DATE: 11/19/07
Obtained at RCSB PDB https://rcsb.org
RCSB Link: https://www.rcsb.org/structure/2VH6