2F53 PDB NFT | MOLNFT bioinformatics, blockchain

Directed Evolution of Human T-cell Receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without apparent cross-reactivity

MOLNFT AF v1 smart contract in GenesisL1 blockchain:

0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba

IPFS of NFT metadata:

bafybeibjwqzttsblccncieqj2sci5r5pxxwuecw7nxq7frt7ukj7ntyjum/metadata.json

IPFS of structure file:

bafybeibbrd3ylvemjzwegaarzdgoepcnuawhxkyp6h6lv4v7ufzt375skm/2f53.pdb

MOLNFT PDB v1

NFT id:
36418
PDB ID:
2F53
Name:
Directed Evolution of Human T-cell Receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without apparent cross-reactivity
Keywords:
IMMUNE SYSTEM
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.10

NFT data

MolNFT PDB v1 is The Protein Data Bank database (URL: https://rcsb.org) of protein structures minted as ERC-721 NFT tokens on GenesisL1 blockchain for public free use, research and entertainment:

H.M. Berman, J. Westbrook, Z. Feng, G. Gilliland, T.N. Bhat, H. Weissig, I.N. Shindyalov, P.E. Bourne.
(2000) The Protein Data Bank Nucleic Acids Research, 28: 235-242.

MOLNFT 2F53 research and analysis (ICN3D with VR)

FASTA sequences

>2f53_A mol:protein length:275 HLA class I histocompatibility antigen
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWE
>2f53_B mol:protein length:100 Beta-2-microglobulin
MIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPCIVKWDRDM
>2f53_C mol:protein length:9 Cancer/testis antigen 1B
SLLMWITQC
>2f53_D mol:protein length:193 T-cell Receptor, alpha chain
MKQEVTQIPAALSVPEGENLVLNCSFTDSAIYNLQWFRQDPGKGLTSLLLIPFWQREQTSGRLNASLDKSSGRSTLYIAASQPGDSATYLCAVRPTSGGSYIPTFGRGTSLIVHPYIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFN
>2f53_E mol:protein length:243 T-cell receptor, beta chain
NAGVTQTPKFQVLKTGQSMTLQCAQDMNHEYMSWYRQDPGMGLRLIHYSVSVGMTDQGEVPNGYNVSRSTTEDFPLRLLSAAPSQTSVYFCASSYVGNTGELFFGEGSRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQDPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD

References and links

Current molecular structure file and data about current molecular structure file and NFT token based on it with
PDBID: 2F53
TITLE: Directed Evolution of Human T-cell Receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without apparent cross-reactivity
DOI: 10.1110/ps.051936406
AUTHORS: Rizkallah, P.J., Jakobsen, B.K., Dunn, S.M., Sami, M.
ACCESSION DATE: 11/25/05
Obtained at RCSB PDB https://rcsb.org
RCSB Link: https://www.rcsb.org/structure/2F53