1T8I PDB NFT

Human DNA Topoisomerase I (70 Kda) In Complex With The Poison Camptothecin and Covalent Complex With A 22 Base Pair DNA Duplex

MOLNFT AF v1 smart contract in GenesisL1 blockchain:

0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba

IPFS of NFT metadata:

bafybeidboq5kcwcd3uirhsf3uymchg6qenoamgow65knmzkavdmlbnayly/metadata.json

IPFS of structure file:

bafybeigs7cn7orgy752cpmwyjmbu6dmicatyfxssdt76hljql2nd5l5qlu/1t8i.pdb

MOLNFT PDB v1

NFT id:
22549
PDB ID:
1T8I
Name:
Human DNA Topoisomerase I (70 Kda) In Complex With The Poison Camptothecin and Covalent Complex With A 22 Base Pair DNA Duplex
Keywords:
ISOMERASE/DNA
Experimental Method:
X-RAY DIFFRACTION
Resolution:
3.00

NFT data

MolNFT PDB v1 is The Protein Data Bank database (URL: https://rcsb.org) of protein structures minted as ERC-721 NFT tokens on GenesisL1 blockchain for public free use, research and entertainment:

H.M. Berman, J. Westbrook, Z. Feng, G. Gilliland, T.N. Bhat, H. Weissig, I.N. Shindyalov, P.E. Bourne.
(2000) The Protein Data Bank Nucleic Acids Research, 28: 235-242.

MOLNFT 1T8I research and analysis (ICN3D with VR)

FASTA sequences

>1t8i_B mol:na length:10 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T)-3'
AAAAAGACTT
>1t8i_C mol:na length:12 5'-D(*(TGP)P*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3'
GGAAAAATTTTT
>1t8i_D mol:na length:22 5'-D(*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*CP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3'
AAAAATTTTTCCAAGTCTTTTT
>1t8i_A mol:protein length:592 DNA topoisomerase I
KKPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDAKKEQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF

References and links

Current molecular structure file and data about current molecular structure file and NFT token based on it with
PDBID: 1T8I
TITLE: Human DNA Topoisomerase I (70 Kda) In Complex With The Poison Camptothecin and Covalent Complex With A 22 Base Pair DNA Duplex
DOI: 10.1021/jm049146p
AUTHORS: Staker, B.L., Feese, M.D., Cushman, M., Pommier, Y., Zembower, D., Stewart, L., Burgin, A.B.
ACCESSION DATE: 05/12/04
Obtained at RCSB PDB https://rcsb.org
RCSB Link: https://www.rcsb.org/structure/1T8I