1R49 PDB NFT

Human topoisomerase I (Topo70) double mutant K532R/Y723F

MOLNFT AF v1 smart contract in GenesisL1 blockchain:

0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba

IPFS of NFT metadata:

bafybeigii45s4bjue7yniqxo6h37m6uubrwlbecxnibt62yfj5vl5hd7ei/metadata.json

IPFS of structure file:

bafybeifwikcqdtpftnkonhxqujhkz36xndjppoxufrt5idzdmve2kep6dy/1r49.pdb

MOLNFT PDB v1

NFT id:
20099
PDB ID:
1R49
Name:
Human topoisomerase I (Topo70) double mutant K532R/Y723F
Keywords:
ISOMERASE/DNA
Experimental Method:
X-RAY DIFFRACTION
Resolution:
3.13

NFT DeSci data

MolNFT PDB v1 is The Protein Data Bank database (URL: https://rcsb.org) of protein structures minted as ERC-721 NFT tokens on GenesisL1 blockchain for public free use, research and entertainment:

H.M. Berman, J. Westbrook, Z. Feng, G. Gilliland, T.N. Bhat, H. Weissig, I.N. Shindyalov, P.E. Bourne.
(2000) The Protein Data Bank Nucleic Acids Research, 28: 235-242.

MOLNFT 1R49 research and analysis (ICN3D with VR)

FASTA sequences

>1r49_B mol:na length:22 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*AP*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3'
AAAAAGACTTAGAAAAATTTTT
>1r49_C mol:na length:22 5'-D(P*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3'
AAAAATTTTTCTAAGTCTTTTT
>1r49_A mol:protein length:592 DNA topoisomerase I
KKPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGRDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDAKKEQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNFLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF

References and links

Current molecular structure file and data about current molecular structure file and NFT token based on it with
PDBID: 1R49
TITLE: Human topoisomerase I (Topo70) double mutant K532R/Y723F
DOI: 10.1074/jbc.M309959200
AUTHORS: Interthal, H., Quigley, P.M., Hol, W.G., Champoux, J.J.
ACCESSION DATE: 10/03/03
Obtained at RCSB PDB https://rcsb.org
RCSB Link: https://www.rcsb.org/structure/1R49