1RR8 PDB NFT

Structural Mechanisms of Camptothecin Resistance by Mutations in Human Topoisomerase I

MOLNFT AF v1 smart contract in GenesisL1 blockchain:

0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba

IPFS of NFT metadata:

bafybeiby7ivzrgtk4ws42kcm23azqey4gfbb7srf5iyujr3y6a56a2expi/metadata.json

IPFS of structure file:

bafybeiandnri7iozl6uem4hbm4bab25bqysqsujnon6vd3ylrzdv7ne3wa/1rr8.pdb

MOLNFT PDB v1

NFT id:
20826
PDB ID:
1RR8
Name:
Structural Mechanisms of Camptothecin Resistance by Mutations in Human Topoisomerase I
Keywords:
ISOMERASE/DNA
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.60

NFT DeSci data

MolNFT PDB v1 is The Protein Data Bank database (URL: https://rcsb.org) of protein structures minted as ERC-721 NFT tokens on GenesisL1 blockchain for public free use, research and entertainment:

H.M. Berman, J. Westbrook, Z. Feng, G. Gilliland, T.N. Bhat, H. Weissig, I.N. Shindyalov, P.E. Bourne.
(2000) The Protein Data Bank Nucleic Acids Research, 28: 235-242.

MOLNFT 1RR8 research and analysis (ICN3D with VR)

FASTA sequences

>1rr8_A mol:na length:22 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T*GP*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3'
AAAAAGACTTGGAAAAATTTTT
>1rr8_B mol:na length:22 5'-D(*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*CP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3'
AAAAATTTTTCCAAGTCTTTTT
>1rr8_C mol:protein length:565 DNA topoisomerase I
AAWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLSRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQQAPPKTFEKSMMNLQTKIDAKKEQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF

References and links

Current molecular structure file and data about current molecular structure file and NFT token based on it with
PDBID: 1RR8
TITLE: Structural Mechanisms of Camptothecin Resistance by Mutations in Human Topoisomerase I
DOI: 10.1016/j.jmb.2004.03.077
AUTHORS: Chrencik, J.E., Staker, B.L., Burgin, A.B., Stewart, L., Redinbo, M.R.
ACCESSION DATE: 12/08/03
Obtained at RCSB PDB https://rcsb.org
RCSB Link: https://www.rcsb.org/structure/1RR8