1E7W PDB NFT

One active site, two modes of reduction correlate the mechanism of leishmania pteridine reductase with pterin metabolism and antifolate drug resistance in trpanosomes

MOLNFT AF v1 smart contract in GenesisL1 blockchain:

0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba

IPFS of NFT metadata:

bafybeievgigimmtzcfxberjwzqgzzivrr7vgip3i3lpy4of37jsdwsaiwm/metadata.json

IPFS of structure file:

bafybeicfnfttd6ixxlib6fq3son3gb6ceiqllb6hdguf3wm5ywb4chkgoe/1e7w.pdb

MOLNFT PDB v1

NFT id:
5105
PDB ID:
1E7W
Name:
One active site, two modes of reduction correlate the mechanism of leishmania pteridine reductase with pterin metabolism and antifolate drug resistance in trpanosomes
Keywords:
OXIDOREDUCTASE
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.75

NFT data

MolNFT PDB v1 is The Protein Data Bank database (URL: https://rcsb.org) of protein structures minted as ERC-721 NFT tokens on GenesisL1 blockchain for public free use, research and entertainment:

H.M. Berman, J. Westbrook, Z. Feng, G. Gilliland, T.N. Bhat, H. Weissig, I.N. Shindyalov, P.E. Bourne.
(2000) The Protein Data Bank Nucleic Acids Research, 28: 235-242.

MOLNFT 1E7W research and analysis (ICN3D with VR)

FASTA sequences

>1e7w_A mol:protein length:291 PTERIDINE REDUCTASE
GSHMTAPTVPVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVDDMPPAVWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLTRA
>1e7w_B mol:protein length:291 PTERIDINE REDUCTASE
GSHMTAPTVPVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVDDMPPAVWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLTRA

References and links

Current molecular structure file and data about current molecular structure file and NFT token based on it with
PDBID: 1E7W
TITLE: One active site, two modes of reduction correlate the mechanism of leishmania pteridine reductase with pterin metabolism and antifolate drug resistance in trpanosomes
DOI: 10.1038/88584
AUTHORS: Gourley, D.G., Hunter, W.N.
ACCESSION DATE: 09/11/00
Obtained at RCSB PDB https://rcsb.org
RCSB Link: https://www.rcsb.org/structure/1E7W